Place of Origin : 
Post Date : 25-10-2021
Expiry Date : 31-12-2022

L-type Ca2+ Channels. Calcicludine Is A Potent And Specific Antagonist Of Neuronal L-type CaV Channels1.

SPECIFICATION OF CALCICLUDINE

Product Name: Calcicludine (Calcicludine, L-type Ca2+ Channel Blocker)
CAT.#: C1020-V
CAS N0.: 178037-96-2
Sequence: WQPPWYCKEPVRIGSCKKQFSSFYFKWTAKKCLPFLFSGCGGNANRFQTIGECRKKCLGK(Disulfide Bonds Between Cys7-Cys57, Cys16-Cys40 And Cys32-Cys53)
Purity: > 98%
Solubility: Any Aqueous Buffer. Centrifuge All Product Preparations Before Use (10000 X G 5 Min).
Form/State: Lyophilized Powder
Molecular Weight: 6979
Molecular Formula: C321H476N86O78S6
Source: Synthetic Peptide
Shipping And Storage: Shipped At Room Temperature. The Product As Supplied Can Be Stored Intact At Room Temperature For Several Weeks. For Longer Periods, It Should Be Stored At -20°C.
Storage Of Solutions: Up To Two Weeks At 4°C Or Three Months At -20°C.

APPLICATION OF CALCICLUDINE

Calcicludine (CAC) Is A 60-amino Acid Polypeptide From The Venom Of Dendroaspis Angusticeps. Calcicludine, A Venom Peptide Of The Kunitz-type Protease Inhibitor Family, Is A Potent Blocker Of High-threshold Ca2+ Channels With A High Affinity For L-type Channels In Cerebellar Granule Neurons.
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