Place of Origin :
Description:
Sulfobutylether b-cyclodextrin is an anionic bcyclodextrin derivative with a sodium sulfonate salt separated from the hydrophobic cavity by a butyl spacer group. The substituent is introduced at positions 2, 3, and 6 in at least one of the glucopyranose units in the cyclodextrin structure. Introducing the sulfobutylether (SBE) into b-cyclodextrin can produce materials with different degrees of substitution, theoretically from 1 to 21;
Characteristics & Applications:
SBE- β –CD is A Chemically Modified Cyclodextrin With A Structure Designed To Optimize The Solubility And Stability Of Drugs.The Amount Of Sulfobutylether β-cyclodextrin That May Be Used Is Dependent On The Purpose For Inclusion In The Formulation, The Route Of Administration, And The Ability Of The Cyclodextrin To Complex With The Drug Being Delivered.
Betadex Sulfobutyl Ether Sodium Salt Is The Sulfonated Modified Sodium Salt Of Beta Cyclodextrin,which Is An Anionic, Highly Water-soluble Cyclodextrin Derivative, Can Be Well Incorporated With Drug Molecules To Form Non-covalent Complexes, Thereby Improving The Stability, Water Solubility And Safety Of The Drug , Reducing Nephrotoxicity, Ease Drug Hemolysis, Control Drug Release Rate, Mask Bad Odor, Etc.
Zhiyuan Biotechnology ulfobutylether B-cyclodextrin Is Derived From B-cyclodextrin, Which Is Nephrotoxic When Administered Parenterally. However, Studies Have Shown That Sulfobutylether Bcyclodextrin Is Well Tolerated At High Doses, When Administered Via Intravenous Bolus Injections, Orally, And By Inhalation. Up To 9 G/day May Be Administered By IV Infusion In A Licensed Voriconazole Formulation. The Safety Following High Doses Of Sulfobutylether β-cyclodextrin Intravenous Administration In Humans Is Continually Being Investigated.
