Place of Origin : Huaian,China
Post Date : 04-01-2024
Expiry Date : 25-12-2024

Hanbon Advanced Chromatography Systems Has Reliable Performance And Flexible Configuration, And Can Provide Bio-Lab® Laboratory Chromatography System, Bio-Pro® Pilot&process Chromatography System, Etc.

Ommon Principles Of Process Scale-Up: Linear Scale-Up
Linear Scale-up Is The Most Common Principle Used In Process Scale-up. By Linear Scale-up, We Mean That We Can Obtain Almost Uniform Bioprocess Chromatography Results From Laboratory Scale To Pilot Results Or Industrial Production Level. The Core Idea Is To Keep The Column Height And Linear Flow Rate Constant And Only Scale Up The Column Diameter And Volume Flow Rate. A Fixed Column Height And Linear Flow Rate Theoretically Ensures The Same Retention Time, The Number Of CVs Used In Chromatography And The Number Of CVs Of The Eluted Sample, Maximizing The Same Purification Results. Theoretically, This Linear Scale-up Of The Purification Separation Behavior Should Be Very Similar, Thus Ensuring A Successful Scale-up Of The Ion Chromatography Process. However, Some Additional Factors Need To Be Considered, Including A Decrease In Column Tube Support (increased Pressure Drop), Column Efficiency/column Bed Instability, Sample Diffusion (peak Spreading), And Dead Volume Of The System And Tubing.

We Provide Chromatography Step By Step Method, Chromatography Purification Method, Chromatography Process Example, Anion Exchange Chromatography Elution, Equipment Used For Chromatography, Etc. For More Information, Please Feel Free To Contact Us!