Place of Origin : Guiyang,China
Post Date : 31-01-2024
Expiry Date : 09-05-2024

Catalog #: AP15072
Name: SN 38
Chemical Formula: C22H20N2O5
Molecular Weight: 392.40
CAS: 86639-52-3
Purity: =95%
Availability: In Stock

SN-38 (7-Ethyl-10-hydroxycamptothecin) CAS: 86639 52 3 AP:15072 SN-38 Is A Chemical Compound That Belongs To The Class Of Camptothecin Derivatives. This Compound Contains Several Functional Groups, Including A Lactone Ring, A Carbonyl Group, And A Tertiary Amine Group.

The Primary Mechanism Of Action Of SN-38 Is Through Inhibition Of Topoisomerase I, An Enzyme That Plays A Critical Role In DNA Replication And Repair. By Preventing Topoisomerase I From Functioning Properly, SN-38 Disrupts The Normal Cellular Processes And Leads To DNA Damage And Apoptosis (programmed Cell Death) In Cancer Cells.

SN-38 Has Been Incorporated Into Various Anti-cancer Drug Formulations, Such As Irinotecan And Topotecan, And Has Shown Remarkable Efficacy In The Treatment Of Various Cancers, Including Colorectal, Lung, And Ovarian Cancers. In Addition, SN-38 Has Also Been Investigated For Its Potential Use In Combination Therapies With Other Anti-cancer Agents, As Well As In The Development Of Targeted Drug Delivery Systems.

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