Histone H2A,Lyophilized,Catalog Number: H1300,Store at -20°C or -80°C - Product

Place of Origin : hefei,China

Product Description

Product Details:
Catalog Number:
H1300
Product Name:
H2A
Scale:
50 µg
Purity:
=95%
Price:
$84
Sequence:
SGRGKQGGKA RAKAKTRSSR AGLQFPVGRV HRLLRKGNYA ERVGAGAPVY LAAVLEYLTA EILELAGNAA RDNKKTRIIP RHLQLAIRND EELNKLLGKV TIAQGGVLPN IQAVLLPKKT ESHHKAKGK
Molecular Formula:
N/A
Molecular Weight:
N/A
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C

Physical Specification

Other Specification :

Histone H2A Catalog Number H1300 Store At -20°C Or -80°C

Histone H2A Is One Of The Four Core Histone Proteins Involved In The Structure Of Chromatin In Eukaryotic Cells. H2A Is Important For Packaging DNA Into Chromatin And Has Been Found To Regulate Gene Expression. This Product Is Expressed In E.coli And Composed Of 129 Amino Acids.

Structure

H2A Consists Of A Main Globular Domain, An N-terminal tail And A C-terminal Tail. Both Tails Are The Location Of post-translational Modification. Thus Far, Researchers Have Not Identified Any Secondary Structures That Arise In The Tails. H2A Utilizes A Protein Fold Known As The ‘histone Fold’. The Histone Fold Is A Three-helix Core Domain That Is Connected By Two Loops. This Connection Forms A ‘handshake Arrangement.’ Most Notably, This Is Termed The helix-turn-helix motif, Which Allows For Dimerization With H2B. The ‘histone Fold’ Is Conserved Among H2A At The Structural Level; However The Genetic Sequence That Encodes For This Structure Differs Between Variants.

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